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Thromboembolic diseases are currently one of the causes that endanger human health and lead to the highest mortality rate, such as myocardial infarction, cerebral thrombosis, deep vein thrombosis, cerebral embolism, pulmonary embolism, etc. In addition, thrombosis is an important pathological process involved in the pathogenesis of many diseases. 1. Anticoagulant therapy (1) Heparin: Heparin is a commonly used anticoagulant and is a highly sulfated glucosaminoglycan. Heparin is widely found in mammalian tissues, and mast cells are the main producing sites. The main sources of medicinal heparin are bovine lung and pig intestinal mucosa. Heparin used clinically is called unfraction heparin (UFH) because it is a mixture of components with different relative molecular weights. The relative molecular weight is between 33,000 and 30,000, which is also called standard heparin (SH). The drug name is heparin sodium. (2) Low molecular weight heparin: crude heparin is cracked into some fraction with relative molecular mass of 1000 ~ 12000 by chemical or enzymatic hydrolysis methods, and then purified. There are at least 10 kinds of low molecular weight heparin prepared by different manufacturers and different methods.In the previous example of electric lights, a state mode program was completed. First, the Light class is defined, which is also called Context here. Then in Light's constructor, to create instance objects for each state class, Context will hold references to these state objects in order to delegate the request to the state objects. The user's request, that is, the action of clicking button, is also implemented in Context, with the following code:东环市公安局重案队正在庆祝“清网行动”取得重大胜利：将一名负案在逃多年的嫌疑人捕获归案。突然得知发生了惊人血案，一名公安民警被歹徒偷袭致重伤，身上的枪和子弹被抢走。公安局立刻派出重案队全力侦破，上级机关也派刑侦副处长高林前来督导破案。高林会同重案队长洪顺达及从重案队调走的派出所干警许毅共同组成专案组。这三人是警校同学，生活中又有着千丝万缕的联系。他们克服了生活中相互之间的种种误会，与案犯斗智斗勇，经过大量的侦查，许毅发现案犯孙志军的父亲曾被自己的父亲抓捕入狱，确定这次是其报复作案。三人及专案组立刻全力对孙进行追捕，通过斗智斗勇的多次较量，终将其围困在山野间，经激烈枪战，临近退休的干警老丁则在紧急关头为保护许毅中弹牺牲。最后许毅亲手将孙志军击毙，成功破获此案。FBI深度卧底组（Deep Cover Operations，简称D.C.O.）特工Martin Odum（Sean Bean）拥有超出常人想象的适应能力——无论执行任何任务，他都能完美地将自己「转化」成不同的人，从而成功混入敌人内部。然而一个神秘的陌生人声称Odum并 不是真正的Odum，令Odum开始质疑自己的真实身份，整个事件变得扑朔迷离。为了帮忙解决朋友的问题，真琴不断以同样的方法回到过去。她突然发现自己手臂上的数字原来是穿越时空的次数，次数变得越来越少，与此同时她也发现了千昭的秘密……紧随其后的是一位年轻的计算机程序员（马利克），他患有社交焦虑症，并通过黑客行为结成了一个神秘的无政府主义者。